Unlocking the Potential of Herbal Immunomodulation: The Rise of Polyherbal Formulations and the Promise of Storg-B

Recent findings in the Journal of Pharmaceutical Research International support Storg-B’s role in enhancing immune response

In today’s world, there’s a notable surge in the adoption of natural remedies, particularly herbal medicines, for immunomodulation.

The undesirable side effects associated with chemical immunomodulators have spurred a quest for safer alternatives. Endorsed by the World Health Organization, herbal medicines offer a compelling solution. They not only stimulate specific and non-specific immunity but also present the advantage of polyherbal formulations, which target multiple pathways simultaneously.

Polyherbal blends are gaining popularity due to their diverse therapeutic uses, presenting advantages superior to those of single herbal formulas. Storg-B stands out as a standardized polyherbal supplement crafted from extracts of medicinal herbs like Psidium guajava, Mangifera indica, and Citrus limon, enriched with natural B vitamins and co-nutrients such as carotenoids and polyphenols.

Recent research underscores the significant role of vitamin B in enhancing immune responses. B vitamins regulate the immune system, each tailored to specific immune cells and functions, serving unique roles in enhancing overall immune health.

Storg-B contains essential B vitamins, including thiamine (B1), riboflavin (B2), niacin (B3), pantothenic acid (B5), pyridoxine (B6), and folate (B9), crucial for supporting various immune functions and promoting overall health.

In a recent study published in the Journal of Pharmaceutical Research International, researchers from Star Hi Herbs Pvt. Ltd. in India explored the impact of Storg-B on the immune system using a cyclophosphamide-induced immunosuppression model in SD rats. The study assessed the effectiveness of this synergized blend in reversing or mitigating the immunosuppressive effects induced by cyclophosphamide in the rats.

Plant-based immunomodulators boost the immune system by activating it non-specifically. This involves B cells interacting with antigens and producing antibodies through the humoral immune system.

After being treated with Storg-B, the production of primary and secondary antibodies increased significantly. These antibodies are crucial in neutralizing antigens or aiding their recognition by phagocytes, leading to the elimination of antigens. Storg-B has been found to enhance the humoral immune response in rats, indicating an increase in the responsiveness of T and B lymphocyte subsets, which play an essential role in antibody formation.

Furthermore, leukocyte count is a key parameter in assessing immune response, and both control and Storg-B-treated groups were evaluated in the study.

Group V, which received Storg-B, displayed the highest count of leukocytes, indicating early activation for a robust immune response. There was a correlation between higher concentrations of Storg-B and significant immunological responses. Neutrophil adhesion to nylon fibers increased, possibly due to β-2 integrin upregulation and reduced corticosterone levels, supported by higher neutrophil percentages. 

Overall, Storg-B shows promise for enhancing humoral immunity, indicating its potential as a therapeutic option for immune-suppressed conditions. The findings illustrate Storg B’s capacity to bolster the humoral immune response to SRBC antigen in rats, highlighting its immune-boosting capabilities. Given its immune-enhancing properties, Storg-B may be beneficial in addressing immunological disorders linked to impaired antioxidant systems.

Interested in formulating with Storg-B? Contact us today to discover how Storg-B can enhance your next immune health product.